The card sets are:
The Thousand-Pixel Cabinet - Classic arcade homages galore!
Quantum Jump - In space, no one can hear you flip cards.
UUUuurrrrrgh! - The obligatory zombie set. These guys just don't give up!
Saved by the 90's - All our favorite pop-culture and TV references from decades past.
Fast - Play your cards furiously with this action-inspired set!
Shonen Leap - These cards are all about the power of friendship.
Deus Rex Machina - Cyberpunk Hackers and Evil Corporations. You've never seen these in a card game before!
A Game of Rings - Explore a magical fantasy world where everyone dies suddenly and brutally.
Developmental Issues - Meet the developers of Millennium Blades!
Penny Dreadful - Old-style mystery meets mafia shootouts.
The Ultimate Steel Cook - Deckbuild with a new flavor with these famous chefs!
Ultimate Kaiju Throwdown - Remember kids, only you can destroy Tokyo.
Set Rotation also includes several other new cards:
6 new starter decks, based on card types instead of elements
The Great War (soldiers)
The Academy (mages)
Gods & Myths (myths)
Future Perfect (constructs)
Animal Farm (animals)
Four new playable characters
Pritchard Leftfield - A game designer who dabbles in time travel, and the original creator of Millennium Blades.
The Card Shark
Friendly Alien Lettstrade
Nine new promo sets (3 bronze, 3 silver, 3 gold)
Four co-op mode decks